Decontamination procedures (cleansing and sporicidal disinfection) need to render the interior surfaces and demanding zone on the isolator free of viable microorganisms. The design and improvement of a decontamination cycle ordinarily takes place on completion from the OQ. USP3 again supplies steerage on this subject matter as does PIC/S6 https://tailinscitech.wixsite.com/tailinscitech/post/vhp-sterilization-solutions-by-tailin-bioengineering-protecting-pharma-and-laboratory-environments