Gastrointestinal (GI): NSAIDs that block COX-one action have correlations with GI problems as a result of inhibition on the synthesis of gastroprotective brokers including PGE2 and also other prostaglandins. This inhibition results in reduced mucin production by gastric epithelial cells, considerably less bicarbonate secretion, and fewer epithelial mobile turnover, between https://joycem420jtc9.wikifiltraciones.com/user